Table 1.
Susceptibility of C. innocuum and other clostridia to several antibiotics
| MIC90 (μg/ml) | ||||
|---|---|---|---|---|
| Antimicrobial Agent | C. innocuum (n=21) | C. perfringens (n=11) | C. ramosum (n=20) | C. clostridioforme (n=20) |
| Penicillin G | 8 | 2 | 8 | 32 |
| Metronidazole | 1 | 2 | 1 | 0.125 |
| Clindamycin | 1 | 2 | 4 | 1 |
| Cefoxitin | 128 | 2 | 64 | 32 |
| Cefotetan | >128 | 1 | 64 | 8 |
| Imipenem | 4 | 0.5 | 1 | 4 |
| Meropenem | 2 | 1 | 4 | 2 |
| Amoxicillin-clavulanate | 0.5 | 0.25 | 0.25 | 0.5 |
| Ampicillin-sulbactam | 0.5 | 0.25 | 1 | 2 |
| Piperacillin-tazobactam | 2 | 1 | 1 | 16 |
| Vancomycin | 8 | 0.25 | 2 | 0.25 |
Table adapted from [8]. Clinical isolates were cultured from blood, intra-abdominal and soft tissue infections, and obtained from the R. M. Alden Culture Collection and from the Anaerobe Reference Unit.