Table 1.
Genes identified as misspliced in Srsf2/SRSF2 mutant cells in at least 10 of 16 datasets
| Gene | Description | No. of datasets (human/murine) |
|---|---|---|
| ATF2 | Activating transcription factor 2 | 13 (7H/6M) |
| MTMR14 | Myotubularin related protein 14 | 13 (9H/4M) |
| HNRNPA2B1 | Heterogenous nuclear ribonucleoprotein A2/B1 | 11 (5H/6M) |
| SEC24B | SEC24 family member B | 11 (6H/5M) |
| AGTPBP1 | ATP/GTP binding protein 1 | 10 (5H/5M) |
| PRPSAP2 | Phosphoribosyl pyrophosphate synthetase-associated protein 2 | 10 (6H/4M) |
| EHMT2 | Euchromatic histone-lysine N-methyltransferase 2 | 10 (5H/5M) |
| STRADA | STE20-related kinase adaptor α | 10 (5H/5M) |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 10 (5H/5M) |
| MTF2 | Metal response element binding transcription factor 2 | 10 (5H/5M) |
| RSRC2 | Arginine/serine-rich coiled-coil 2 | 10 (7H/3M) |
| CEP57 | Centrosomal protein 57kDa | 10 (8H/2M) |
| FIP1L1 | Factor interacting with PAPOLA and CPSF1 | 10 (7H/3M) |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 10 (6H/4M) |
| ABI1 | Abl-interactor 1 | 10 (6H/4M) |
| HUWE1 | HECT, UBA, and WWE domain containing 1, E3 ubiquitin protein ligase | 10 (5H/5M) |
| TPD52L2 | Tumor protein D52-like 2 | 10 (8H/2M) |
| ZMYND8 | Zinc finger, MYND-type containing 8 | 10 (7H/3M) |
| NSD1 | Nuclear receptor binding SET domain protein 1 | 10 (5H/5M) |
Genes are ranked by the number of datasets the transcript was identified in. The number of human (H) or murine (M) datasets is indicated in parentheses.