Table 1.
All patients, n (%) | |
---|---|
Patients, n | 26 |
Age at infusion, years (range) | 14.4 (4.0-24.5) |
Male | 15 (58) |
Follow-up, d (range) | 389 (53-800) |
MRD-negative CR on d 28 | 20 (77) |
Indication for CAR T therapy | |
Primary refractory | 4 (15) |
Relapse | 22 (85) |
Disease status at start of lymphodepletion | |
M1 marrow | 17 (65) |
≥M2 marrow | 9 (35) |
Prior lines of systemic therapy, n | |
1-2 | 21 (81) |
3-5 | 5 (19) |
Prior blinatumomab | |
Yes | 7 (27) |
No | 19 (73) |
Prior allo-HCT | |
Yes | 11 (42) |
No | 15 (58) |
TP53 mutation | |
Yes | 2 (8) |
No | 24 (92) |