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Significant factors affecting overall survival (OS) according to univariate analysis. (a) Tumor length (1 = <5 cm, 2 = ≥5 cm); (b) T staging (1 = T1 + T2, 3 = T3 + T4); (c) N staging (1 = N0, 2 = N1, 3 = N2 + N3); (d) TNM staging (1 = stage I, 2 = stage II, 3 = stage III); and (e) vascular tumor invasion (0 = no, 1 = yes). COX-2, cyclooxygenase-2.
