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. 2022 Apr 13;101(6):1282–1286. doi: 10.1016/j.kint.2022.04.009

Figure 1.

Figure 1

Increase in anti-spike antibody levels after the third dose of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine in kidney transplant recipients (KTRs). (a,b) Total antibody (IgM, IgG, and IgA) mean fluorescence intensity (MFI) ratios to wild-type (WT) SARS-CoV-2 antigens before and after the third vaccine dose in KTRs (n = 51; a) and in prepandemic healthy controls (HCs; n = 5) and prepandemic kidney transplant control patients (KCs; n = 15), measured by Luminex-based multiplex assay (b). (c,d) Antibody MFI ratios for anti-spike antibodies of WT and variants of SARS-CoV-2 before and after the third vaccine dose in KTRs (c) and prepandemic HCs and KCs (d). Horizontal lines indicate positivity threshold for assay. (e,f) Proportion of KTRs with anti-spike antibodies against WT and variants of SARS-CoV-2 before (e) and after (f) the third vaccine dose. (a,c) Statistic by Wilcoxon matched-pairs signed rank test. (e,f) Statistic by χ2 test. NC, nucleocapsid; RBD, receptor-binding domain.