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. 2022 Apr 13;8:2. doi: 10.1186/s40733-022-00084-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — A Correlation between serum C1M level and blood neutrophils. Data were analysed using spearman’s correlation (r = 0.273, p < 0.0001). B Patients were stratified into high versus low blood neutrophils levels based on the median. C1M was significantly increased in patients with high neutrophil levels (n = 109) compared to low (n = 82) (p = 0.0154). C C1M was significantly increased in obese (BMI > 30) patients (n = 49) compared to normal-weight (BMI < 25) patients (n = 65) (p = 0.0137). D Obese asthmatics with high blood neutrophils (n = 33) had a significant increase in C1M compared to normal-weight asthmatics with low blood neutrophils (n = 36) (p = 0.0026). Data are presented as a Tukey box plot and analyzed using the Mann-Whitney test. Asterisks indicate statistically significance: *p < 0.05, **p < 0.01