Table 2.
Protein methylations in human mitochondria (from PhosphoSitePlus)
| Category | Total | Mitochondrial |
|---|---|---|
| All proteins | 20,386 | 1234 |
| Methylated proteins | 5447 (26.7%a) | 385 (31.2%a) |
| Methylations | 15,919 | 775 |
| Methylations per protein | 2.9 | 2.0 |
| Arg methylations | 10,806 (67.9%b) | 525 (67.7%b) |
| - Rme1 | 0.86 | 0.94 |
| - Rme2 | 0.14 | 0.06 |
| Lys methylations | 5101 (32.0%b) | 248 (32.0%b) |
| - Kme1 | 0.83 | 0.80 |
| - Kme2 | 0.11 | 0.11 |
| - Kme3 | 0.06 | 0.09 |
| Other methylations | 12 (0.1%b) | 2 (0.3%b) |
Data on human protein methylation were downloaded from PhosphoSitePlus (in Sept. 2021). Methylations were designated as "mitochondrial" when the corresponding protein is annotated with a mitochondrial localization in UniProt. For Arg and Lys methylations, the fraction constituted by each individual methylation state is indicated.
a
of all proteins.
b
of all methylations.