Table 2. Clinical Outcomes and Severity among Children and Adolescents Hospitalized with Covid-19.*.
| Characteristic | Children 5–11 Yr | Adolescents 12–18 Yr | ||||
|---|---|---|---|---|---|---|
| Total (N = 267) |
Unvaccinated (N = 247) |
Fully Vaccinated (N = 20)† |
Total (N = 918) |
Unvaccinated (N = 796) |
Fully Vaccinated (N = 122)† |
|
| ICU admission — no./total no (%) | 60/262 (23) | 55/244 (23) | 5/18 (28) | 326/912 (36) | 306/790 (39) | 20/122 (16) |
| Critical Covid-19 — no./total no. (%)‡ | 42/259 (16) | 38/241 (16) | 4/18 (22) | 249/910 (27) | 232/789 (29) | 17/121 (14) |
| Invasive mechanical ventilation | 18/259 (7) | 17/241 (7) | 1/18 (6) | 96/905 (11) | 88/784 (11) | 8/121 (7) |
| Noninvasive mechanical ventilation | 26/258 (10) | 24/240 (10) | 2/18 (11) | 195/907 (21) | 182/786 (23) | 13/121 (11) |
| Vasoactive infusion | 11/259 (4) | 9/241 (4) | 2/18 (11) | 75/908 (8) | 69/787 (9) | 6/121 (5) |
| Extracorporeal membrane oxygenation | 2/259 (1) | 2/241 (1) | 0/18 | 22/907 (2) | 21/786 (3) | 1/121 (1) |
| Death before discharge from hospital | 1/249 (<1) | 1/232 (<1) | 0/17 | 13/879 (1) | 11/765 (1) | 2/114 (2) |
| Median hospital length of stay (IQR) — days§ | 2 (1–5) | 2 (1–5) | 3 (1–3) | 4 (2–7) | 4 (2–8) | 3 (2–5) |
*
ICU denotes intensive care unit.
†
Patients were described as being fully vaccinated if they had received a second dose of the BNT162b2 vaccine at least 14 days before the onset of illness.
‡
Critical Covid-19 was defined as Covid-19 leading to life support (i.e., noninvasive mechanical ventilation [bilevel positive airway pressure or continuous positive airway pressure] or invasive mechanical ventilation, vasoactive infusions, or extracorporeal membrane oxygenation) or death.
§
Data on length of hospital stay were missing for 20 children 5 to 11 years of age (17 unvaccinated and 3 fully vaccinated) and for 58 adolescents 12 to 18 years of age (47 unvaccinated and 11 fully vaccinated).