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. 2022 Apr 11;9(1):e000611. doi: 10.1136/lupus-2021-000611

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Metformin improves the survival and renal function in experimental lupus nephritis. (A) The survival ration of lupus mice with or without 8 weeks of metformin treatment. (B) The body weight of lupus mice. (C) The concentration of urinary proteins of lupus mice. (D) The level of serum creatinine of lupus mice. (E) The level of serum blood urea nitrogen (BUN) of lupus mice. Each bar represents the mean±SEM from at least three independent experiments versus control, **p<0.01.