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. 2022 Mar 30;13:879020. doi: 10.3389/fphar.2022.879020

FIGURE 1.

FIGURE 1

Tamoxifen therapeutic regimen according to on- or off-target indications. Tamoxifen is administered at different concentrations and timings according to on-target, ERα-dependent or off-target, ERα-unrelated indications and may reach micromolar drug concentrations in patient plasma or tissues.