Table 3.

Overview of the essential residues for H⁺- and Na⁺-binding of the translocating subunit in V-type ATPases (Murata et al., 2005).

Residue	E. hirae	H+-coupled	H. elongata	P. furiosus	A. xylanus
139	E	E	E	E	E
61	L	M	M	L	L
64	T	I	T	T	T
65	Q	I	Q	Q	Q
110	Q	I	Q	Q	Q
68	Y	Y	L	Y	Y

Notable differences from E. hirae (Na⁺) in H. elongata are marked ind boldface.