TABLE 1.
Nucleic acid differences of viral genome sequences of HRTVs
| Segment | Nucleotide position (cRNA orientation) | Nucleotide difference by straina |
Amino acid change | |||
|---|---|---|---|---|---|---|
| HRTV-MO-4-NIID | wtHRTV | pRF-HRTV-L | rwtHRTV | |||
| L | 273 | G/A | G | A | A | G86E |
| L | 1060 | G | G | A | A | Synonymous |
| L | 2217 | A | A/G | A | A/G | N734S |
| L | 3309 | A/T | T/A | A | A | Y1098F |
| L | 6231 | C/G | G/C | G | G | T2072R |
a
Sequences represented by “x/y” indicate that the nucleic acid sequence of this nucleotide position was a mixture of “x” and “y” and the major nucleic acid was “x.”