TABLE 1.

Pharmacokinetic parameters of total ¹⁴C-radioactivity in human plasma.

	tmax (h)	Cmax (ng-eq/ml)	AUC0-∞ (ng-eq*h/ml)	t1/2 (h)
Geometric mean (95% CI)	1.5 (1.0-3.0) a	325 (240-439)	3,759 (2,738-5,162)	34.6 (16.8-71.4)
CVln (%)	-	29	31	78

^aData is displayed as median (range).

AUC_0-∞, area under the plasma concentration-time curve from 0 to infinity; CI, confidence interval; C_max, maximum plasma concentration; CV_ln, geometric coefficient of variation; t_1/2, terminal half-life; t_max, time to reach maximum plasma concentration.