TABLE 2.
Compound ID | Plasma | Urine | Feces | Urine + feces | ||
---|---|---|---|---|---|---|
% in sample | % in sample | % of dose a | % in sample | % of dose a | % of dose | |
ACT-1004-1239 | 53.9 | 69.6 | 10.1 | 7.5 | 5.2 | 15.3 |
M1 | 10.3 | 9.7 | 1.4 | 34.1 | 23.7 | 25.1 |
M23 | 21.1 | - | - | - | - | - |
A1 | - | - | - | 5.8 | 4.0 | 4.0 |
A2 | - | - | - | 22.0 | 15.3 | 15.3 |
A3 | - | - | - | 3.9 | 2.7 | 2.7 |
Other b | 14.7 | 20.7 | 3.0 | 26.7 | 18.6 | 21.6 |
Total | - | - | 14.5 | - | 69.6 | 84.1 |
Calculations were based on geometric mean of total cumulative excretion in urine/feces.
Refers to the sum of metabolites with a relative abundance of <5%.