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. 2022 Mar 22;12:835626. doi: 10.3389/fonc.2022.835626

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Copyright © 2022 Llera, Abdelhay, Artagaveytia, Daneri-Navarro, Müller, Velazquez, Alcoba, Alonso, Alves da Quinta, Binato, Bravo, Camejo, Carraro, Castro, Castro-Cervantes, Cataldi, Cayota, Cerda, Colombo, Crocamo, Del Toro-Arreola, Delgadillo-Cisterna, Delgado, Dreyer-Breitenbach, Fejerman, Fernández, Fernández, Fernández, Franco-Topete, Gabay, Gaete, Garibay-Escobar, Gómez, Greif, Gross, Guerrero, Henderson, Lopez-Muñoz, Lopez-Vazquez, Maldonado, Morán-Mendoza, Nagai, Oceguera-Villanueva, Ortiz-Martínez, Quintero, Quintero-Ramos, Reis, Retamales, Rivera-Claisse, Rocha, Rodríguez, Rosales, Salas-González, Sanchotena, Segovia, Sendoya, Silva-García, Trinchero, Valenzuela, Vedham, Zagame, United States-Latin American Cancer Research Network (US-LACRN) and Podhajcer

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytolytic score CYT and survival analysis according to PAM50 subtypes in the MPBCS cohort. (A), distribution of CYT among PAM50 subtypes. Medians were compared using the Kruskal-Wallis test (p= 2.2e-16). Adjusted p-values for the paired comparisons using Dunn’s test are defined as follows: *< 0.05, **< 0.01, ****< 0.0001. (B, C), Kaplan-Meier curves and survival analysis for cancer-related overall survival (OSC) according to a binary assignation of high (i.e. above median) and low CYT to LumA (B) and Basal (C) tumors. (D, E), Kaplan-Meier curves and survival analysis for disease-free survival (DFS) according to the same binary assignation of high (i.e. above median) and low CYT to LumA (D) and Basal (E) tumors.