Figure 3.

Cut-Point Ranges. * Denotes study found at least one significant relationship between 25(OH)D status and risk of breast cancer by any receptor status. + Denotes study which used binary cut-points. ++ Quintile values were provided through communication with the author and did not appear In the published article. Each cohort used a slightly different range of values, so results are stratified in this figure. +++ Graph shows highest cut-point range though 50 ng/ml. Upper limits in studies are not known and could be higher or lower. (Ref) Reference standards. From left to right, colored sections indicate deficiency, insufficiency, and sufficiency. High ranges were truncated at 50 ng/mL for clarity. Upper levels of sufficiency established by the Institute of Medicine, Endocrine Society, and Vitamin D Council are 50 ng/mL, 100 ng/mL, and 80 ng/mL, respectively.