Table 1.
Intrinsic Subtype | Clinico-pathologic definition | Immunohistochemistry Status |
Prognosisc | ||
---|---|---|---|---|---|
ER and/or PR | HER2 overexpression | Ki-67 | |||
| |||||
Luminal A | Luminal A | Positive | No | Low | Good |
Luminal B | Luminal B (HER2 negative) | Positive | No | High | Intermediate |
Luminal B (HER2 positive) | Positive | Yes | Any | Poor | |
HER2 overexpressionb | HER2 positive (nonluminal) | Absent | Yes | Not defined | Poor |
Basal-like | Triple negative (ductal) | Absent | No | Not defined | Very Poor |
Table adapted from St Gallen International Expert Consensus Panel (3).
Listed in original source as "Erb-B2 overexpression".
Prognoses adapted from Dai 2015 (5).