FIGURE 10.

KL Tg expression reduces Wnt‐signaling in Pax7+ cells during early postnatal muscle growth. (A, B) Sections of Wt (A) and KL Tg+ (B) quadriceps muscle at P14 labeled with anti‐Pax7 (red), anti‐β‐catenin (green), and DNA labeled with DAPI (blue). *Indicates Pax7+ cells also expressing active β‐catenin+. Open arrowheads (>) indicate Pax7+ single‐labeled cells. Bar = 10 μm. (C) Ratio of Pax7+ cells that showed activated β‐catenin relative to total Pax7+ cells in Wt and KL Tg+ quadriceps muscles. *Indicates significantly different from age‐matched Wt at p < .05 analyzed by t‐test. Error bar represents SEM. N = 5 for each data set