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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Brain Behav Immun. 2022 Jan 19;101:288–303. doi: 10.1016/j.bbi.2022.01.013

Table 2.

Statistical results from cytokine analyses presented in Figs. 2 and 8.

Cytokine Statistics

Fig. 2 t-test Two-way ANOVA Post-hoc


Interaction Sex TCDD Female Male





P value Test Stat P value Test Stat P value Test Stat P value Test Stat P value Test Stat P value Test Stat

Tnf-α p < 0.0001 t(32) = 5.294 p = 0.0381 F (1, 31) = 4.691 p = 0.8159 F (1,31) = 0.05511 p < 0.0001 F (1,31) = 20.98 p = 0.1738 t(31) = 1.768 p = 0.0001 t(31) = 4.617
11–6 p = 0.0045 t(33) = 3.052 p = 0.0009 F (1, 31) = 13.59 p = 0.0004 F (1,31) = 16.12 p < 0.0001 F (1, 31) = 24.39 p = 0.7329 t(31) = 0.9165 p < 0.0001 t(31) = 5.903
Il-lβ p < 0.0001 t(33) = 5.210 p = 0.2913 F (1, 31) = 1.152 p = 0.6248 F (1, 31) = 0.2440 p < 0.0001 F (1, 31) = 25.02 p = 0.0144 t(31) = 2.877 p = 0.0005 t(31) = 4.158
iNos p = 0.0236 t(33) = 2.374 p = 0.0235 F (1, 31) = 5.679 p = 0.0845 F (1, 31) = 3.176 p = 0.0053 F (1, 31) = 8.976 p > 0.9999 t(31) = 0.4489 p = 0.0018 t(31) = 3.681
Arg p = 0.0080 t(33) = 2.822 p = 0.1787 F (1,31)= 1.893 p = 0.2725 F (1, 31) = 1.248 p = 0.0043 F (1, 31) = 9.509 p = 0.4409 t(31) = 1.251 p = 0.0093 t(31) = 3.052
Fig. 8 Two-way ANOVA Post-hoc
Interaction Repopulation TCDD Control PLX (Repopulation)
P value Test Stat P value Test Stat P value Test Stat P value Test Stat P value Test Stat
Tnf-α p = 0.0059 F (1, 20) = 9.477 p = 0.3386 F (1,20) = 0.9613 p = 0.0519 F (1, 20) = 4.274 p = 0.0031 t(20) = 3.665 p = 0.9719 t(20) = 0.7099
Il-6 p = 0.0001 F (1, 20) = 22.08 p = 0.0088 F (1, 20) = 8.432 p = 0.0046 F (1, 20) = 10.16 p < 0.0001 t(20) = 5.617 p = 0.6025 t(20) = 1.061
Il-1β p = 0.0002 F (1, 20) = 21.06 p = 0.0014 F (1, 20) = 13.64 p = 0.0011 F (1, 20) = 14.55 p < 0.0001 t(20) = 5.985 p > 0.9999 t(20) = 0.5438
iNos p = 0.0066 F (1, 20) = 9.199 p = 0.0315 F (1, 20) = 5.350 p = 0.1417 F (1, 20) = 2.341 p = 0.0080 t(20) = 3.249 p = 0.6077 t(20) = 1.055
Arg p = 0.0002 F (1, 20) = 21.49 p = 0.0023 F (1, 20) = 12.15 p = 0.0011 F (1, 20) = 14.47 p < 0.0001 t(20) = 6.011 p > 0.9999 t(20) = 0.5842