Table 5.
Sensitivity, specificity, Youden index, cutoff points, and AUC (95% CI) for each index in predicting diabetes risk among adults in China.
| Cut-off | AUC (95% CI) | Sensitivity (%) | Specificity (%) | Youden index | |
|---|---|---|---|---|---|
| Total | |||||
| TyG | 8.41 | 0.597 (0.559, 0.636) | 74.11 | 41.91 | 16.02 |
| TyG-BMI | 209.89 | 0.644 (0.605, 0.682) | 58.88 | 64.43 | 23.31 |
| TyG-WC | 764.61 | 0.642 (0.603, 0.682) | 57.87 | 67.15 | 25.02 |
| TyG-WHtR | 4.99 | 0.658 (0.619, 0.696) | 52.28 | 72.86 | 25.14 |
| VAI | 77.02 | 0.603 (0.565, 0.641) | 52.28 | 59.17 | 11.45 |
| LAP | 32.75 | 0.635 (0.597, 0.674) | 59.39 | 62.61 | 22.00 |
| TG/HDL-C | 0.98 | 0.565 (0.526, 0.604) | 50.25 | 56.76 | 7.01 |
| TC/HDL-C | 3.95 | 0.557 (0.517, 0.597) | 52.28 | 57.22 | 9.50 |
| NFG | |||||
| TyG | 8.47 | 0.558 (0.481, 0.635) | 46.43 | 59.33 | 5.76 |
| TyG-BMI | 211.42 | 0.565 (0.481, 0.648) | 42.86 | 73.99 | 16.85 |
| TyG-WC | 783.71 | 0.585 (0.499, 0.671) | 39.29 | 81.13 | 20.42 |
| TyG-WHtR | 4.54 | 0.613 (0.527, 0.700) | 60.71 | 60.60 | 21.31 |
| VAI | 77.79 | 0.568 (0.491, 0.644) | 42.86 | 66.30 | 9.16 |
| LAP | 31.13 | 0.601 (0.528, 0.684) | 51.79 | 67.91 | 19.70 |
| TG/HDL-C | 0.69 | 0.532 (0.454, 0.610) | 62.50 | 41.63 | 4.13 |
| TC/HDL-C | 3.45 | 0.526 (0.448, 0.605) | 55.36 | 45.68 | 1.04 |
| IFG | |||||
| TyG | 8.56 | 0.562 (0.517, 0.606) | 69.50 | 40.86 | 10.36 |
| TyG-BMI | 222.56 | 0.643 (0.601, 0.685) | 51.06 | 68.26 | 19.32 |
| TyG-WC | 764.61 | 0.630 (0.586, 0.674) | 63.12 | 58.31 | 21.43 |
| TyG-WHtR | 4.99 | 0.639 (0.596, 0.682) | 56.74 | 65.14 | 21.88 |
| VAI | 67.49 | 0.590 (0.547, 0.633) | 65.25 | 47.89 | 13.14 |
| LAP | 29.36 | 0.619 (0.576, 0.662) | 69.50 | 51.00 | 20.50 |
| TG/HDL-C | 0.99 | 0.552 (0.507, 0.596) | 56.03 | 51.35 | 7.38 |
| TC/HDL-C | 3.89 | 0.544 (0.497, 0.590) | 59.57 | 49.19 | 8.76 |
AUC, area under curve; CI, confidence interval; NFG, normal fasting glucose; IFG, impaired fasting glucose; TyG, triglyceride glucose; TyG-BMI, TyG related to body mass index; TyG-WC, TyG related to waist circumference; TyG-WHtR, TyG related to waist-to-height ratio; VAI, visceral adiposity index; LAP, lipid accumulation product; TG/HDL-C, triglyceride to high-density lipoprotein cholesterol ratio; TC/HDL-C, total cholesterol to high-density lipoprotein cholesterol ratio.