FIGURE 2.

BETi treatment effects on the inducible expression of inflammatory genes in lipopolysaccharide (LPS)‐stimulated peripheral blood mononuclear cells (PBMCs) from Fabry disease patients. Quantification of the indicated gene expression changes driven by apabetalone in PBMCs (enzyme replacement therapy, n = 7) using quantitative RT‐PCR. Bar graphs show the mean ± SEM. On the x‐axis, apa = apabetalone. Statistical significance was determined by one‐way repeated measures ANOVA followed by Dunnett's multiple comparison test compared with LPS+DMSO. *p < .05, **p < .01, ***p < .001, ****p < .0001