TABLE 1.
Genotype and allele frequencies of five CLEC16A variants in PD patients and controls.
| Variant | Genotype, n (%) | P | Allele, n (%) | P | OR (95%CI) | |||
|---|---|---|---|---|---|---|---|---|
| rs6498169 | GG | GA | AA | 0.005 a | G | A | 0.042 | 1.199 (1.007–1.427) |
| Control | 151 (30.0) | 264 (52.4) | 89 (17.7) | 566 (56.2) | 442 (43.8) | |||
| PD | 150 (29.1) | 232 (45.0) | 133 (25.8) | 532 (51.7) | 498 (48.3) | |||
| rs12708716 | AA | AG | GG | 0.430 | A | G | 0.288 | 1.116 (0.912–1.366) |
| Control | 293 (58.1) | 186 (36.9) | 25 (5.0) | 772 (76.6) | 236 (23.4) | |||
| PD | 288 (55.9) | 192 (37.3) | 35 (6.8) | 768 (74.6) | 262 (25.4) | |||
| rs12917716 | GG | GC | CC | 0.055 | G | C | 0.026 | 1.221 (1.024–1.456) |
| Control | 173 (34.3) | 258 (51.2) | 73 (14.5) | 604 (59.9) | 404 (40.1) | |||
| PD | 154 (29.9) | 259 (50.3) | 102 (19.8) | 567 (55.0) | 463 (45.0) | |||
| rs7200786 | AA | AG | GG | 0.004 a | A | G | 0.044 | 1.207 (1.005–1.448) |
| Control | 220 (43.7) | 239 (47.4) | 45 (8.9) | 679 (67.4) | 329 (32.6) | |||
| PD | 216 (41.9) | 218 (42.3) | 81 (15.7) | 650 (63.1) | 380 (36.9) | |||
| rs2903692 | GG | GA | AA | 0.731 | G | A | 0.732 | 1.036 (0.846–1.268) |
| Control | 289 (57.3) | 188 (37.3) | 27 (5.4) | 766 (76.0) | 242 (24.0) | |||
| PD | 286 (55.5) | 204 (39.6) | 25 (4.9) | 776 (75.3) | 254 (24.7) | |||
a
P < 0.01. CI, confidence interval; OR, odds ratio; PD, Parkinson’s disease.