TABLE 4.
The highest-risk haplotype analysis of CLEC16A in association with PD.
| Variants, n | Haplotype a | Control, n (%) | PD, n (%) | P | OR (95%CI) |
|---|---|---|---|---|---|
| 5 | AAGAG | 93.3 (9.26) | 120.9 (11.74) | 0.02 | 1.47 (1.06–2.04) |
| 4 | AAG-G | 96.7 (9.59) | 129.4 (12.56) | 0.011 | 1.54 (1.11–2.15) |
| 3 | AA--G | 185.1 (18.36) | 233.1 (22.63) | 0.0047 | 1.42 (1.11–1.82) |
| 2 | A---G | 218.0 (21.63) | 264.8 (25.71) | 0.017 | 1.32 (1.05–1.65) |
a
Haplotype alleles were in the order of rs6498169, rs12708716, rs12917716, rs7200786, and rs2903692. Haplotypes with frequency <3% in both PD patients and controls were excluded from the analysis. A hyphen indicates the eliminated variant at that position.
CI, confidence interval; OR, odds ratio; PD, Parkinson’s disease.