Table 3.
Risk of Bias
| Author, Year | Was the Randomization Sequence Adequately Generated? | Was Allocation Adequately Concealed? | Was There Blinding of Participants? | Was There Blinding of Caregivers? | Was There Blinding of Data Collectors? | Was There Blinding of Staticians? | Was There Blinding of Outcome Assessors? | Was Loss to Follow-Up (Missing Outcome Data) Infrequent?* | Are Reports of the Study Free of Suggestion of Selective Outcome Reporting? | Was The Study Apparently Free of Other Problems That Could Put It at a Risk of Bias? |
|---|---|---|---|---|---|---|---|---|---|---|
| Amr 201028 | Probably yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Probably yes | Definetely yes | Probably yes | Definetely yes | Definetely yes |
| Amr 201127 | Probably yes | Definetely yes | Definetely yes | Definetely yes | Probably yes | Probably yes | Probably yes | Probably yes | Definetely yes | Definetely yes |
| Barros 201229 | Probably yes | Probably yes | Definetely yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Definetely yes | Probably yes |
| Eide, 199438 | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Definetely yes | Probably yes |
| Fallon, 201833 | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Definetely not | Definetely yes | Definetely yes |
| Kim, 201531 | Probably yes | Probably yes | Definetely yes | Probably yes | Probably yes | Probably yes | Definetely yes | Definetely yes | Probably yes | Probably yes |
| Kvarnstrom, 200335 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Probably yes |
| Lauretti, 200241 | Probably yes | Probably yes | Definetely yes | Probably yes | Probably yes | Probably yes | Probably yes | Definetely yes | Definetely yes | Probably yes |
| Lynch, 200536 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely not | Probably yes | Probably yes |
| Max, 199539 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Probably yes |
| Mercadante, 200040 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Probably yes |
| Niesters, 201330 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes |
| Pickering, 201934 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes |
| Rigo, 201732 | Probably yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Probably not | Definetely yes | Definetely yes |
| Scwartzman, 200926 | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably yes | Probably not | Probably yes | Probably yes |
| Sigtermans, 200925 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Probably yes |
| Vranken, 200537 | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes | Definetely yes |