Table 3.

Echocardiographic parameters at the beginning and the follow-up visits.

	Basal	Visit 1	Visit 2	Visit 3	Visit 4
N (patients)	85	85	84	83	77
LVEF [%]	67.13 ± 5.9	64.74 ± 5.6*	63.26 ± 5.1*	64.05 ± 5.3*	60.89 ± 7.0*
GLS [%]	18.91 ± 2.8	18.32 ± 3.5	17.67 ± 3.7	17.63 ± 3.3	18.1 ± 3.2

Values expressed as mean ± standard deviation;

^*indicates p-value < 0.05 compared to baseline values.

The global longitudinal strain (GLS) is expressed in absolute values; LVEF — left ventricular ejection fraction measured by the Simpson method