FIG. 1.

(A) Results from QC-PCR analysis for viral DNA load in peripheral blood lymphocytes. Data are expressed as copies per 10 ng of DNA (approximately 1,600 lymphocytes). Each point designates an individual animal with samples measured at 4, 8, and 12 weeks p.i. Open circles denote FIV-infected, saline-treated cats, and closed circles denote FIV-infected, ZDV-treated cats. Means and SDs for each group of data points are represented by horizontal and vertical bars, respectively. Differences between the ZDV-treated FIV-infected and saline-treated FIV-infected groups were statistically significant at weeks 8 (P = 0.015) and 12 (P = 0.001). PBMC, peripheral blood mononuclear cells. (B) Results from QC-RT-PCR analysis for viral RNA in plasma from the 10-week-p.i. point. Data are expressed as copies per milliliter of plasma. Each point designates an individual animal. Open circles denote FIV-infected, saline-treated cats, and closed circles denote FIV-infected, ZDV-treated cats. Means and SDs for each group of data points are represented by horizontal and vertical bars, respectively. The difference between the ZDV-treated FIV-infected and saline-treated FIV-infected groups was statistically significant (P = 0.0087).