Table 6. The Partial Correlation Adjusted for Age between Cognitive Tests and Other Parameters. Significance Level was Considered as P<0.05.
MMSE | CDR | ADAS-cog | NPI-severity | NPI-caregiver distress | ||||||
r | P-value | r | P-value | r | P-value | r | P-value | r | P-value | |
Aβ 40 | -0.185 | 0.266 | 0.122 | 0.476 | 0.167 | 0.317 | 0.399 | 0.026* | 0.4 | 0.026* |
TNF-α | -0.27 | 0.106 | 0.416 | 0.013* | 0.236 | 0.161 | -0.29 | 0.12 | -0.338 | 0.068 |
IL-1α | -0.124 | 0.458 | -0.076 | 0.651 | 0.386 | 0.017* | -0.095 | 0.61 | -0.15 | 0.419 |
TNF-α/ IL-10 ratio | -0.35 | 0.037* | 0.077 | 0.657 | 0.091 | 0.599 | -0.082 | 0.672 | -0.114 | 0.556 |
PGE2 | -0.405 | 0.012* | 0.358 | 0.027* | 0.209 | 0.208 | 0.136 | 0.465 | 0.29 | 0.114 |
NPI-caregiver distress | -0.333 | 0.068 | 0.363 | 0.045* | 0.449 | 0.019* | 0.885 | 0.000* | - | - |
TSH | 0.223 | 0.185 | -0.215 | 0.202 | -0.307 | 0.065 | -0.454 | 0.023* | -0.437 | 0.029* |
Aβ: Amyloid-beta; TNF-α: Tumor Necrosis Factor α; IL-1α: Interleukin-1α; IL-10: Interleukin-10; PGE2: Prostaglandin E2; TSH: Thyroid Stimulating Hormone; MMSE: Mini-Mental State Examination; CDR: Clinical Dementia Rating; ADAS-cog: Alzheimer’s Disease Assessment Scale-cognitive subscale; NPI- severity: Neuropsychiatric Inventory-severity; NPI- caregiver distress: Neuropsychiatric Inventory- caregiver distress. *Significant Correlation