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. 2021 Jan 25;10:e1974. doi: 10.31661/gmj.v10i0.1974

Table 6. The Partial Correlation Adjusted for Age between Cognitive Tests and Other Parameters. Significance Level was Considered as P<0.05.

MMSE CDR ADAS-cog NPI-severity NPI-caregiver distress
r P-value r P-value r P-value r P-value r P-value
Aβ 40 -0.185 0.266 0.122 0.476 0.167 0.317 0.399 0.026* 0.4 0.026*
TNF-α -0.27 0.106 0.416 0.013* 0.236 0.161 -0.29 0.12 -0.338 0.068
IL-1α -0.124 0.458 -0.076 0.651 0.386 0.017* -0.095 0.61 -0.15 0.419
TNF-α/ IL-10 ratio -0.35 0.037* 0.077 0.657 0.091 0.599 -0.082 0.672 -0.114 0.556
PGE2 -0.405 0.012* 0.358 0.027* 0.209 0.208 0.136 0.465 0.29 0.114
NPI-caregiver distress -0.333 0.068 0.363 0.045* 0.449 0.019* 0.885 0.000* - -
TSH 0.223 0.185 -0.215 0.202 -0.307 0.065 -0.454 0.023* -0.437 0.029*

Aβ: Amyloid-beta; TNF-α: Tumor Necrosis Factor α; IL-1α: Interleukin-1α; IL-10: Interleukin-10; PGE2: Prostaglandin E2; TSH: Thyroid Stimulating Hormone; MMSE: Mini-Mental State Examination; CDR: Clinical Dementia Rating; ADAS-cog: Alzheimer’s Disease Assessment Scale-cognitive subscale; NPI- severity: Neuropsychiatric Inventory-severity; NPI- caregiver distress: Neuropsychiatric Inventory- caregiver distress. *Significant Correlation