Table 3.

Univariable and multivariable analyses for factors associated with overall graft survival

	Univariable analysis			Multivariable analysis
	HR	95%CI	P	HR	95%CI	P
Recipient preoperative factors
Recipient age, per 10 years*	1.041	0.839–1.313	0.723
Recipient sex, male	0.628	0.354–1.097	0.103
Positive 3 body composition marker	7.232	2.918–15.503	<0.001	6.883	2.704–15.374	<0.001†
Fulminant hepatic failure	1.783	0.433–4.864	0.371
MELD, per 1 score*	1.023	0.990–1.054	0.168
AST, per 1 IU/L*	0.999	0.994–1.003	0.762
ALT, per 1 IU/L*	0.999	0.993–1.003	0.845
Total bilirubin, mg/dL*	1.008	0.976–1.034	0.612
Albumin, g/dL*	1.276	0.807–2.006	0.296
Creatinine, mg/dL*	1.135	0.866–1.351	0.303
Donor factors
Donor age ≥40 years	1.704	0.949–3.214	0.075	1.403	0.767–2.681	0.277
GRWR <0.6%	2.609	0.903–5.982	0.073	2.016	0.694–4.666	0.178
Blood type incompatible donor	2.007	1.114–3.523	0.021	1.854	1.012–3.297	0.046†
Intraoperative parameters
Blood loss, per 1L*	0.992	0.949–1.008	0.672
Cold ischemia time, per 1 h*	0.937	0.752–1.119	0.508
P/F ratio at the start of operation <300	1.068	0.595–2.015	0.830
P/F ratio at the start of operation <400	1.031	0.581–1.799	0.581
cFiO2 ≥0.5	1.868	1.004–3.331	0.047	1.897	1.007–3.432	0.048†
Final PVP ≥15 mmHg	1.013	0.414–2.129	0.976

^*The factor is included in the analysis as continuous data. Calculated FiO₂ (cFiO₂) was defined as {O₂(L) + Air(L) × 0.21}/{O₂(L) + Air(L)}. †P <0.05 on multivariate analysis. ALT alanine aminotransferase; AST aspartate aminotransferase; CI confidence interval; EAD early allograft dysfunction; FiO₂ fraction of inspiratory oxygen; GRWR graft-to-recipient weight ratio; HR hazard ratio; MELD model for end-stage liver disease; P/F PaO₂/FiO₂ ratio; PVP portal vein pressure