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KAT6B epigenetically promotes STAT3 expression in glioma cells. (a) The expression of STAT3 was measured by RT-PCR assay and Western blot analysis in U251 and LN229 cells treated with shKAT6B. (b) The enrichment of KAT6B on STAT3 promoter was analyzed by ChIP assay. (c, d) The U251 and LN229 cells were treated with shKAT6B. The enrichment of H3K23ac (c) and RNA pol II (d) on STAT3 promoter was analyzed by ChIP assay. ∗∗p < 0.01.
