Table 2.
Effect of ashwagandha extract on the onset time to sleep and duration of sleep using the pentobarbital sleep-induction model
Group | Onset time to sleep (latency time, min) | Duration of sleep (min) |
---|---|---|
Control | 53.13±1.62 | 59.75±1.11 |
Positive control (diazepam) | 25.13±0.48* | 101.88±1.22* |
Ashwagandha extract (low dose) | 48.13±0.55#§ | 66.88±1.09#§ |
Ashwagandha extract (mid-dose) | 42.38±0.56*§† | 76.38±1.13*§‡ |
Ashwagandha extract (high dose) | 35.13±0.35*§†∥ | 87.75±1.47*§†∥ |
Data are presented as mean±SEM.
*P<0.0001 and #P=0.002 compared with control.
§P<0.0001 compared with positive control.
†P<0.0001 and ‡P=0.0003 compared with ashwagandha low dose.
∥P<0.0001 compared with ashwagandha mid-dose.