Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 6;604(7905):310–315. doi: 10.1038/s41586-022-04558-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 4 — (A) Graphical display of the percentage of all protein-coding genes (blue) and of the subset of clinical genes (orange) that have a defined MANE Select transcript per each MANE project release over time. (B) Number of genes that have a defined MANE Select transcript (MANE v0.95). The list includes 101 genes that will require the MANE Select to be defined using an ALT or PATCH (rather than the GRCh38 Primary Assembly). It does not include an additional set of 345 genes that require review due to conflicting gene types between RefSeq and Ensembl/GENCODE.