Skip to main content
. Author manuscript; available in PMC: 2023 Apr 12.
Published in final edited form as: Circulation. 2022 Feb 10;145(15):1108–1119. doi: 10.1161/CIRCULATIONAHA.121.056305

Table 3.

Correlations Between Regional Brain Volume Residuals and Neurodevelopmental Outcomes in the CHD Group

Bayley-III ABAS-3
Cognitive Composite Receptive Communication Expressive Communication Fine Motor Gross Motor General Adaptive Composite
Total brain volume (per ml)* 0.40** 0.32* 0.40** 0.41** 0.42** 0.47***
 Fetal cortex 0.36* 0.29* 0.23 0.43** 0.34* 0.43**
 All white matter 0.33* 0.26 0.41** 0.31* 0.36* 0.39**
 Proliferative compartments 0.30* 0.21 −0.02 0.44** 0.27 0.31*
 Subcortical gray matter 0.30* 0.24 0.42** 0.13 0.30* 0.16
 Diencephalon 0.11 0.17 0.33* 0.11 0.17 0.13
 Brain stem 0.16 0.16 0.17 0.18 0.28 0.31*
 Cerebellum 0.22 0.25 0.41** 0.22 0.31* 0.25

Total brain volume refers to residual after adjustment of fetal total brain volume for sex and gestational age (linear and quadratic terms)

*

P<0.05

**

P<0.01

***

P<0.001

Bayley-III = Bayley Scales of Infant Development, Third Edition

ABAS-3 = Adaptive Behavior Assessment System, Third Edition