Skip to main content
. Author manuscript; available in PMC: 2023 Apr 30.
Published in final edited form as: Stat Med. 2022 Jan 24;41(9):1644–1657. doi: 10.1002/sim.9319

FIGURE 4.

FIGURE 4

Manhattan Plot of G × E p-values (on the -log10 scale) from the taxane-anthracycline chemotherapy study in Section 4 using weighted Bonferroni testing. G × E p-values for each loci are arranged left to right in ascending order of their respective conditional p-values. Loci marked by a black dot or triangle represent G×E p-values that passed the subset-adjusted significance threshold (red dotted line). As a comparison, the standard GWIS significance threshold is also included (blue dotted line) with the black dot indicating a significant finding.