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Hypersensitive and Slowly Desensitizing responses in Chrna9Ĺ9T knockin mice. (A) Acetylcholine is more potent in α9α10 nAChRs of mutant mice; (B) Hair cell responses to 1 mM ACh during 1 min show slower desensitization kinetics in mutant mice; (C) Spontaneous synaptic MOC-hair cell currents are prolonged in mutant mice. Adapted from Taranda et al (2009)12 under Creative Commons Attribution (CC BY) license.
