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. 2022 Mar 31;13:846248. doi: 10.3389/fimmu.2022.846248

Table 2.

Therapies used in patients with autoimmune and inflammatory RMDs.

GC cDMARD bDMARD Anti-CD20 BLySi JAKi
All patients with aiRMDs, n = 89 16 (18%) 43 (48%) 35 (39%) 8 (9%) 2 (2%) 1 (1%)
RA, n = 41 3 (7%) 17 (41%) 18 (44%) 4 (10%) 0 1 (2%)
PsA, n = 7 0 2 (29%) 5 (71%) 0 0 0
AxSpa, n = 12 0 1 (8%) 11 (92%) 0 0 0
SLE n = 11 4 (36%) 9 (8%) 0 0 2 (18%) 0
SS n = 4 1 (25%) 4 (100%) 0 0 0 0
IIM n= 1 1 (100%) 1 (100%) 0 1 (100%) 0 0
SSc n = 1 0 0 0 1 (100%) 0 0
LVV, n = 5 3 (60%) 3 (60%) 1 (20%) 0 0 0
AAV, n = 6 3 (50%) 5 (83%) 0 2 (33%) 0 0
Other vasculitis, n = 1 1 (100%) 1 (100%) 0 0 0 0

Data are presented as n (%). AAV, antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis; aiRMD, autoimmune and inflammatory rheumatic and musculoskeletal disease; AxSpA, axial spondyloarthritis; IIM, idiopathic inflammatory myositis; LVV, large vessel vasculitis; PsA, psoriatic arthritis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus, SS, Sjögren syndrome; SSc, systemic sclerosis; GC, glucocorticoids; cDMARD, conventional DMARD, namely, methotrexate, leflunomide, azathioprine, chloroquine, hidroxychloroquin; bDMARD, biological DMARD, namely, tumor necrosis factor alpha inhibitors (12 patients with RA and 8 patients with AxSpa and 2 patients with PsA), interleukin 17 inhibitors (3 patients with AxSpa and 3 patients PsA), interleukin 6 inhibitors (6 patients with RA and 1 patients with LVV); LySi, BLyS-specific inhibitor, belimumab; JAKi, janus kinase inhibitor.