TABLE 8.

Outline of CD44-targeted therapy using nanogels.

Material	Therapeutic agents	Types of study (in vitro/in vivo)	Cancer types	Cell lines	Animal model	References
Cholesteryl chloroformate and HA	ETO, SAL, and CUR	In vitro	Breast	MDA-MB-231 and MIA PaCa-2	—	Wei et al. (2013)
FA	DOX and cisplatin	Both	Breast	MCF-7/ADR	BALB/c mice	Ma et al. (2021)
Zein	Curcumin	Both	Colon	CT26 and NIH3T3 normal cells	Mice	Seok et al. (2018)
HA-ATRA	Dox	In vitro	Hepatic	HepG-2 and 293 T cells	—	Ma et al. (2018)