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Demographics of the study population. 455 participants were involved in this study, biochemical detection including serum vitamin D, ALP, P1NP and CTX as well as DXA-BMD measurement of the 455 participants were analyzed (Part 1). 113 participants including 55 males and 58 females were screened for GM 16S sequencing and analyses (Part 2), further 57 samples from the above 113 samples were selected for GM metagenome sequencing and analyses (Part 3).
