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L-F001 inhibits RSL3-induced JNK activation in HT22 cells. HT22 cells were treated with 0.1 μM RSL3 alone, and then added L-F001(1–10 μM) at 37°C for 24 h. The levels of P-JNK and JNK were measured by Western blot, and the amount of P-JNK and JNK were estimated by densitometric analysis of each protein band (n = 3). ###P < 0.001 compared with the control group. *P < 0.05 and **P < 0.01 compared with the RSL3 group.
