FIGURE 1.

Validation of the experimental model with drug administration and the observation of the reconnections between lymphatic vessels and transferred lymph nodes. (A,B) Example of the reconnection between lymphatic vessels and lymph nodes. (C,D) Reconnections between lymph nodes with afferent and efferent lymphatics were not fully established and leakage exists. (E,F) Reconnection between lymphatic vessels and lymph nodes in the OVX + TMX group. Stained afferent lymphatic vessels (black arrows) and efferent lymphatic vessels (green arrows). (G) Quantification of lymphatic reconnections of three groups. (H) Quantification of surviving transferred lymph nodes of three groups. (I) Average sizes of transferred PLNs in each group in the largest cross sections. *p < 0.05, **p < 0.01, ***p < 0.001.