Table 2.
Factors | Univariate analysis HR (95% CI) | P value | multivariate analysis HR (95% CI) | P value |
---|---|---|---|---|
gender | ||||
female | 1 | |||
male | 0.853 (0.363-2.004) | 0.715 | ||
age | ||||
<50 | 1 | |||
50-59 | 0.952 (0.419-2.166) | 0.907 | ||
≥60 | 0.246 (0.204-1.503) | 0.246 | ||
Child-Pugh | ||||
A | 1 | |||
B | 1.208 (0.521-2.802) | 0.659 | ||
C | 1.110 (0.253-4.863) | 0.890 | ||
hepatic encephalopathy | ||||
no | 1 | |||
yes | – | – | ||
ascites | ||||
no | 1 | 1 | ||
yes | 2.611 (1.157-5.892) | 0.021 | 1.774 (0.614-5.126) | 0.289 |
TBIL | ||||
<20.5umol/L | 1 | |||
≥20.5umol/L | 0.811 (0.380-1.729) | 0.588 | ||
albumin | ||||
≥35g/L | 1 | |||
<35g/L | 1.163 (0.523-2.586) | 0.710 | ||
Thrombin time | ||||
<18s | 1 | |||
≥18s | 2.723 (0.808-9.178) | 0.106 | ||
HB | ||||
≥110g/L | 1 | |||
<110g/L | 0.893 (0.380-2.100) | 0.795 | ||
PLT | ||||
≥100×109/L | 1 | |||
<100×109/L | 1.722 (0.815-3.640) | 0.154 | ||
ALT | ||||
<50×U/L | 1 | |||
≥50×U/L | 0.962 (0.454-2.038) | 0.920 | ||
HBV DNA | ||||
negative | 1 | 1 | ||
positive | 3.451 (1.309-9.102) | 0.012 | 2.597 (0.936-7.207) | 0.067 |
AFP | ||||
<20ug/L | 1 | 1 | ||
≥20ug/L | 3.631 (1.449-9.097) | 0.006 | 2.393 (0.638-8.975) | 0.196 |
Tumor stage | ||||
BCLC A | 1 | |||
BCLC B | 1.283 (0.288-5.706) | 0.743 | ||
BCLC C | 2.894 (0.628-13.340) | 0.173 |