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. 2022 Mar 31;12:833884. doi: 10.3389/fonc.2022.833884

Table 2.

Subgroup analysis of patients with OS.

Factors Univariate analysis HR (95% CI) P value multivariate analysis HR (95% CI) P value
gender
 female 1
 male 0.853 (0.363-2.004) 0.715
age
 <50 1
 50-59 0.952 (0.419-2.166) 0.907
 ≥60 0.246 (0.204-1.503) 0.246
Child-Pugh
 A 1
 B 1.208 (0.521-2.802) 0.659
 C 1.110 (0.253-4.863) 0.890
hepatic encephalopathy
 no 1
 yes
ascites
 no 1 1
 yes 2.611 (1.157-5.892) 0.021 1.774 (0.614-5.126) 0.289
TBIL
 <20.5umol/L 1
 ≥20.5umol/L 0.811 (0.380-1.729) 0.588
albumin
 ≥35g/L 1
 <35g/L 1.163 (0.523-2.586) 0.710
Thrombin time
 <18s 1
 ≥18s 2.723 (0.808-9.178) 0.106
HB
 ≥110g/L 1
 <110g/L 0.893 (0.380-2.100) 0.795
PLT
 ≥100×109/L 1
 <100×109/L 1.722 (0.815-3.640) 0.154
ALT
 <50×U/L 1
 ≥50×U/L 0.962 (0.454-2.038) 0.920
HBV DNA
 negative 1 1
 positive 3.451 (1.309-9.102) 0.012 2.597 (0.936-7.207) 0.067
AFP
 <20ug/L 1 1
 ≥20ug/L 3.631 (1.449-9.097) 0.006 2.393 (0.638-8.975) 0.196
Tumor stage
 BCLC A 1
 BCLC B 1.283 (0.288-5.706) 0.743
  BCLC C 2.894 (0.628-13.340) 0.173