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. 2022 Mar 31;13:858557. doi: 10.3389/fphar.2022.858557

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Copyright © 2022 Robinson, Redwood and Creaney.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Synergy between chemotherapy and immunotherapy. Mice were injected with mesothelioma AB1-HA tumor cells and then treated on day nine with 120 ug/Gram gemcitabine intraperitoneally and/or 100 ug of FGK45 (activating anti-CD40) three times. Groups of mice received indicated treatment regimens; control animals were treated with PBS (A) Tumor growth rates and (B) survival curves. Arrows represent the start of treatment. Figure originally published in Nowak et al., 2003b. Journal of Immunology 170; 4905-4913.