Predictors in the Model	Coefficient	Standard Error	t	95% CI	P-value
Outcome: Perceptions of Social Distancing Effectiveness
Experimental condition	.01	.03	.28	−.06; .08	.778
Baseline perceptions	.80	.01	53.66	.77; .83	<.001
Age	−.0003	.002	−.18	−.003; 0.003	.856
Education (ref: college+)	.04	.04	1.13	−.03; .11	.257
Race (ref: white)	−.01	.04	−.21	−.09; .08	.834
Hispanic (ref: yes)	.01	.06	.08	−.12; .13	.934
Gender (ref: male)	.03	.03	.73	−.04; .09	.463
Employment (ref: not having to go to work)	−.04	.04	−1.10	−.11; .03	.273
Living area (ref: city/suburb)	.04	.04	1.04	−.03; .11	.298
COVID-19 experience (ref: no)	−.05	.07	−.79	−.18; .08	.431
COVID-19 news following	.002	.01	.13	−.02; .03	.897
Flu shot (ref: no)	.03	.04	.84	−.04; .10	.400
Mask wearing in one’s community	.08	.03	3.08	.03; .14	.002
Political views	−.05	.01	−4.70	−.07; −.03	<.001
Health condition (ref: none)	−.06	.04	−1.32	−.14; .03	.188
Outcome: Intention to social distance
Experimental condition	−.02	.04	−.58	−.09; .05	.563
Baseline intentions	.76	.01	54.57	.73; .79	<.001
Age	.002	.002	1.31	−.001; .01	.190
Education (ref: college+)	.02	.04	.59	−.05; .10	.558
Race (ref: white)	.05	.05	1.05	−.04; .14	.294
Hispanic (ref: yes)	.01	.07	.11	−.13; .14	.910
Gender (ref: male)	−.03	.04	−.81	−.10; .04	.418
Employment (ref: not having to go to work)	−.03	.04	−.81	−.10; .04	.419
Living area (ref: city/suburb)	−.01	.04	−.35	−.09; .06	.726
COVID-19 experience (ref: no)	.13	.07	1.78	−.01; .26	.075
COVID-19 news following	.05	.01	3.42	.02; .08	.001
Flu shot (ref: no)	.06	.04	1.53	−.02; .13	.125
Mask wearing in one’s community	.09	.03	3.28	.04; .15	.001
Political views	−.05	.01	−5.07	−.08; −.03	<.001
Health condition (ref: none)	−.14	.05	−3.15	−.23; −.05	.002
Outcome: Perceptions of vaccine safety and effectiveness
Experimental condition	.04	.03	1.36	−.02; .09	.174
Baseline perceptions	.88	.01	77.86	.86; .91	<.001
Age	.001	.001	1.01	−.001; .004	.314
Education (ref: college+)	.03	.03	1.02	−.03; .09	.308
Race (ref: white)	−.01	.04	−.28	−.08; .06	.780
Hispanic (ref: yes)	−.04	.05	−.82	−.15; .06	.412
Gender (ref: male)	−.02	.03	−.63	−.07; .04	.528
Employment (ref: not having to go to work)	−.01	.03	−.39	−.07; .05	.697
Living area (ref: city/suburb)	−.02	.03	−.56	−.08; .04	.578
COVID-19 experience (ref: no)	.02	.06	.36	−.09; .13	.720
COVID-19 news following	.02	.01	1.90	−.001; .04	.057
Flu shot (ref: no)	.02	.03	.52	−.04; .08	.606
Mask wearing in one’s community	.03	.02	1.15	−.02; .07	.249
Political views	−.03	.01	−3.07	−.04; −.01	.002
Health condition (ref: none)	.004	.04	.11	−.06; .07	.911
Outcome: Intention to receive a vaccine
Experimental condition	.05	.04	1.28	−.02; .12	.199
Baseline intentions	.93	.01	95.04	.92; .95	<.001
Age	−.001	.002	−.62	−.004; .002	.535
Education (ref: college+)	.01	.04	.15	−.07; .08	.879
Race (ref: white)	.01	.05	.24	−.08; .10	.807
Hispanic (ref: yes)	.07	.07	.98	−.07; .20	.326
Gender (ref: male)	−.02	.04	−.53	−.09; .05	.599
Employment (ref: not having to go to work)	.03	.04	.82	−.04; .10	.412
Living area (ref: city/suburb)	−.04	.04	−1.03	−.12; .04	.302
COVID-19 experience (ref: no)	.02	.07	.33	−.11; .16	.739
COVID-19 news following	−.02	.01	−1.79	−.05; .002	.074
Flu shot (ref: no)	.05	.04	1.27	−.03; .13	.204
Mask wearing in one’s community	−.02	.03	−.59	−.07; .04	.558
Political views	−.03	.01	−2.66	−.05; −.01	.008
Health condition (ref: none)	.01	.04	.26	−.08; .10	.793
Outcome: Perceptions about the benefits of unproven drugs
Experimental condition	−.18	.07	−2.69	−.31; −.05	.007
Baseline perceptions	.66	.02	36.26	.62; .69	<.001
Age	.005	.003	1.63	−.001; .01	.104
Education (ref: college+)	.03	.07	.44	−.11; .17	.657
Race (ref: white)	−.06	.08	−.70	−.22; .11	.481
Hispanic (ref: yes)	.32	.13	2.52	.07; .56	.012
Gender (ref: male)	−.03	.07	−.52	−.17; .10	.603
Employment (ref: not having to go to work)	.12	.07	1.75	−.01; .25	.080
Living area (ref: city/suburb)	.05	.07	.70	−.09; .19	.487
COVID-19 experience (ref: no)	.18	.13	1.39	−.07; .43	.165
COVID-19 news following	−.01	.03	−.42	−.06; .04	.673
Flu shot (ref: no)	.08	.07	1.11	−.06; .21	.267
Mask wearing in one’s community	.03	.05	.65	−.07; .14	.513
Political views	.08	.02	4.28	.04; .12	<.001
Health condition (ref: none)	−.03	.08	−.37	−.19; .13	.714
Outcome: Perceptions of importance of clinical trials
Experimental condition	.04	.04	1.06	−.03; .11	.289
Baseline perceptions	.70	.02	40.66	.67; .74	<.001
Age	.003	.002	1.75	−.0003; .01	.081
Education (ref: college+)	−.01	.04	−.26	−.09; .07	.796
Race (ref: white)	.07	.05	1.43	−.02; .16	.153
Hispanic (ref: yes)	.004	.07	.05	−.14; .14	.957
Gender (ref: male)	−.03	.04	−.68	−.10; .05	.498
Employment (ref: not having to go to work)	.02	.04	.45	−.06; .09	.653
Living area (ref: city/suburb)	.01	.04	.29	−.07; .09	.773
COVID-19 experience (ref: no)	−.12	.07	−1.65	−.26; .02	.099
COVID-19 news following	.04	.01	2.47	.01; .06	.013
Flu shot (ref: no)	−.01	.04	−.16	−.08; .07	.872
Mask wearing in one’s community	−.04	.03	−1.52	−.10; .01	.128
Political views	−.06	.01	−5.12	−.08; −.03	<.001
Health condition (ref: none)	−.03	.05	−.58	−.12; .06	.563
Outcome: Willingness to receive an experimental drug
Experimental condition	−.30	.06	−4.99	−.42; −.18	<.001
Baseline willingness	.71	.02	41.59	.68; .74	<.001
Age	.003	.003	1.29	−.002; .01	.198
Education (ref: college+)	.09	.06	1.42	−.03; .22	.155
Race (ref: white)	−.20	.08	−2.55	−.35; .05	.011
Hispanic (ref: yes)	−.02	.12	−.18	−.25; .21	.860
Gender (ref: male)	−.05	.06	−.85	−.17; .07	.398
Employment (ref: not having to go to work)	.06	.06	.95	−.06; .19	.340
Living area (ref: city/suburb)	−.10	.07	−1.43	−.23; .04	.154
COVID-19 experience (ref: no)	.24	.12	2.02	.01; .47	.044
COVID-19 news following	−.003	.02	−.12	−.05; .04	.906
Flu shot (ref: no)	.11	.06	1.71	−.02; .24	.088
Mask wearing in one’s community	−.02	.05	−.50	−.12; .07	.620
Political views	.05	.02	2.92	.02; .09	.004
Health condition (ref: none)	−.07	.08	−.98	−.22; .07	.328