. 2022 Apr 14;2022:3180004. doi: 10.1155/2022/3180004

Table 1.

A review of previously published cases of SAT associated with vaccination against SARS-CoV-2. Only SAT cases from each manuscript are listed in this table.

Reference	Gender	Age	Vaccine	Dose	Time from vaccination until onset of symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-ab
Our case 1	F	36	BNT162b2 (Comirnaty®)	2^nd	1 day	Neck pain, restlessness, fatigue	None	↔	↔	↔	44	Neg	Neg	Neg
Our case 2	M	65	ChAdOx1 (Vaxzevria®)	1^st	3 days	Malaise	None	↔	↔	↓	21	Pos	Neg	Neg
Iremli et al. [11]
Case 1	F	35	PiCoVacc (CoronaVac®)	2^nd	4 days	Left-side anterior neck pain, fever, fatigue, palpitations	None	↑	↔	↔	53	Neg	Neg	Neg
Case 2	F	34	PiCoVacc (CoronaVac®)	1^st	4 days	Anterior neck pain, fever, fatigue, palpitations	None	↑	↓	↓	19	Neg	Neg	Neg
Case 3	F	37	PiCoVacc (CoronaVac®)	2^nd	7 days	Mild anterior neck pain	None	↑	↔	↔	25	Neg	Neg	Neg
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-Ab
Bornemann et al. [12]
Case 1	F	26	ChAdOx1 (Vaxzevria®)	1^st	14 days	Fever, cervical pain radiated in both ears	None	↑	↔	↔	ND	Neg	Neg	Neg
Case 2	F	49	mRNA-1273 (Spikevax®)	1^st	14 days	Sore throat with radiation to the ear, headache	None	↔	↔	↔	ND	Neg	Neg	Neg
Patel et al. [13]
	M	48	ND	2^nd	7 days	Right neck swelling, throat discomfort, palpitations, fever, weight loss	ND	ND	3.6 ng/dl (no RR)	0.01 mIU/L (no RR)	ND	ND	ND	ND
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-ab
Saygili et al. [14]
	F	38	PiCoVacc (CoronaVac®)	2^nd	14 days	Neck swelling, pain, fatigue, loss of appetite, sweating	None	↑	↔	↓	78	Neg	ND	Neg
	F	34	BBV152 (COVAXIN®)	1^st	5–7 days	Fever, palpitation, anterior neck pain	None	↑	↑	↓	60	ND	ND	ND
Chatzi et al. [15]
	F	35	BNT162b2 (Comirnaty®)	1^st	12 days	Neck pain, fatigue, palpations	ND	ND	↑	↓	75	Neg	Neg	Neg
	F	32	BNT162b2 (Comirnaty®)	2^nd	4 days	Neck pain, fatigue	ND	ND	↔	↓	40	Neg	Neg	Neg
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-ab
Kyriacou et al. 10/21 [16]
	F	40	BNT162b2 (Comirnaty ®)	2^nd	12 hours	Malaise, anterior neck pain,	None	ND	↑	↓	67	Pos	Neg	Neg
Siolos et al. [17]
	F	51	BNT162b2 (Corminaty®)	1^st	4 days	Nausea, mild anterior neck pain, fever	None	↔	↑	↓	103	Neg	Neg	Neg
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-ab
Jeeyavudeen et al. [18]
	F	ND	BNT162b2 (Comirnaty®)	2^nd	14 days	Painful swelling, poor sleep, night sweats, hyperdefecation, weight loss	None	↑	↑	↓	ND	Neg	ND	Neg
Plaza-Enriquez et al. [19]
	F	42	mRNA-1273 (Spikevax®)	2^nd	5–6 days	Earache radiating down to the neck and jaw,	None	↑	↔	↓	81	ND	ND	Neg
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-ab
Khan et al. [20]
	F	42	BNT162b2 (Comirnaty®)	2^nd	4 days	Fever, palpitations, painful left-sided neck swelling	ND	ND	↑	↓	60	ND	Neg	Neg
Sözen et al. [21]
	M	41	BNT162b2 (Comirnaty®)	2^nd	8 days	Anterior neck pain, fatigue, palpitation	None	↑	↑	↓	32	Neg	Neg	Neg
	F	40	BNT162b2 (Comirnaty®)	1^st	6 days	Neck pain, palpitation, sweating	None	↔	↔	↓	34	Pos	Neg	Neg
	M	40	BNT162b2 (Comirnaty®)	1^st	4 days	Neck pain, nervousness, fatigue	None	↔	↔	↔	15	Neg	ND	Neg
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-Ab
	F	26	BNT162b2 (Comirnaty®)	2^nd	6 days	Neck pain	None	↑	↑	↓	34	Pos	Neg	Pos
	F	44	BNT162b2 (Comirnaty®)	2^nd	9 days	Neck pain, headache, palpitation, sweating, tremor	Hashimoto thyroiditis	↔	↔	↓	44	Neg	Neg	Pos
Schimmel et al. [22]
	F	57	BNT162b2 (Comirnaty®)	2^nd	1 day	Anterior neck pain, swelling	None	↔	↔	↓	ND	Neg	Neg	Neg
Franquemont et al. [23]
	F	42	BNT162b2 (Comirnaty®)	1s^t	5 days	Sore throat, palpitations	None	11.8 (no RR)	4.58 (no RR)	<0.01 (no RR)	62	Neg	Neg	Neg
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-ab
Oyibo et al. [24]
	F	55	ChAdOx1 (Vaxzevria®)	1^st	21 days	Headache, sore throat, generalized aches, palpitations	None	ND	↑	↓	51	ND	ND	Neg
Sahin Tekin et al. [25]
	M	67	PiCoVacc (CoronaVac®)	2^nd	19 days	Fever, mild neck pain,	None	↑	↑	↓	67	Neg	Neg	Neg
Reference	Gender	Age	Vaccine	Dose	Days until symptoms	Symptoms	History of thyroid disease	fT3	fT4	TSH	ESR (mm) (RR < 15)	TgAb	TRAb	TPO-ab
Pla Peris et al. [26]
	M	67	mRNA-1273 (Spikevax®)	1^st	10–14 days	Neck pain radiating to the ears, asthenia, mild fever, tachykardia	None	ND	↑	↓	60	Neg	Neg	Pos
	M	47	BNT162b2 (Comirnaty®)	1^st	10–14 days	Neck pain radiating to the ears, asthenia, mild fever, tachykardia	None	ND	↔	↓	70	Neg	Neg	Neg

Note: the pathological values are printed in bold. fT3: free triiodothyronine; fT4: free thyroxine; TSH: thyroid-stimulating hormone; ESR: erythrocyte sedimentation rate; TgAb: antithyroglobulin antibody; TRAb, TSH receptor antibodies; TPO-Ab: thyroid peroxidase antibody; pos: positive; neg: negative; ND: no data; RR : reference range; ↔: normal; ↑: increased; ↓: decreased.