Table 3.

Known antiviral activities of human defensins against group IV viruses [21].

Virus\Defensin	HNP1	HNP2	HNP3	HNP4	HD5	HD6	HBD1	HBD2	HBD3	HBD4
Enveloped	-	-	-	-	-	-	-	-	-	-
HCV	Prevent viral entry	Prevent viral entry	Prevent viral entry	Prevent viral entry	*	*	Prevent viral entry	Prevent viral entry	Prevent viral entry	Prevent viral entry
Nonenveloped	-	-	-	-	-	-	-	-	-	-
Picornavirus	-	-	-	-	-	-	-	-	-	-
Coxsackievirus	*	*	*	*	*	*	*	*	U	*
Echovirus	U	*	*	*	*	*	*	*	*	*
Enterovirus	*	*	*	*	*	*	*	*	Prevent viral entry	*
Poliovirus	*	*	*	*	*	*	*	*	U	*
HRV	*	*	*	*	*	*	*	NE	*	*

NE: Tested HDP had no effect, U: Antiviral mechanism is undetermined,

^*:Yet to be tested.

Table shows most common result of HDP antiviral test.