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. 2022 Mar 31;12:717926. doi: 10.3389/fonc.2022.717926

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Copyright © 2022 Yang, Chen, Wang, Wang, Zhang, Yue, Zheng, Li, Bian and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relationship between the clinicopathological characteristics, cluster 1/2 groups and risk score in the TCGA dataset. (A) The heatmap displays the differential distribution of clinicopathological features and eleven pyroptosis-related gene expression levels in gliomas with low and high risk. (B–E) The WHO grade (B), age (C), fustat (D), and cluster 1/2 subgroups (E) stratify the TCGA dataset, and the distribution of risk scores is shown. ***p < 0.001. (F, G) Univariate (F) and multivariate (G) analyses for the TCGA cohort including age, gender, WHO grade and risk score.