Table 1.
One hundred and forty-four pyroptosis-related genes collected from published literature.
| TIGAR | NOD2 | NEDD4 | BAX | ZBP1 | BRD4 | RIPK3 | TP53 |
|---|---|---|---|---|---|---|---|
| PRKACB | ADCY4 | DPP8 | SOD1 | MAPK8 | CLEC4E | TNFRSF4 | MAP3K7 |
| PDCD4 | TICAM1 | GSDMA | PTGER2 | DDX3X | NLRC5 | BRCC3 | CTSB |
| RHEB | CARD8 | NLRP9 | POP1 | ADRA2B | HDAC6 | HSPA12A | HIF1A |
| TYK2 | TLR2 | NFKB2 | NLRC4 | BNIP3 | HK1 | HMOX1 | NEK7 |
| STAT1 | FOXO1 | GZMA | PRKACA | RELA | FADD | KCNK6 | IRGM |
| CASP4 | CYCS | ATG7 | GSDMD | RIPK1 | LDLR | NLRP2 | AOAH |
| NLRP1 | DAPK3 | CASP9 | NFKB1 | MAPK1 | IRF1 | AIM2 | SERPINB1 |
| RELB | TRAF6 | PDCD6IP | PRKAA1 | GBP3 | CASP6 | PYDC2 | NAIP |
| P2RX4 | IRF2 | P2RX7 | IL18 | PELI2 | GSDMC | SDHB | GSDMB |
| SENP6 | EP300 | PCSK9 | IL1β | NLRP3 | TNF | TOMM20 | IRAK1 |
| IFI16 | SENP7 | MUL1 | MEFV | NFE2L2 | CD63 | TXNIP | DHX9 |
| IRF8 | PRKACG | TLR3 | KLF2 | IL13 | GPX4 | MALT1 | CAMP |
| GBP2 | NOS2 | NLRP12 | IRF3 | JOSD2 | NLRX1 | PYCARD | PANX1 |
| SARM1 | CASP3 | NLRP7 | JAK1 | CASP5 | TLR4 | REL | RHOA |
| IRAK4 | NR1H2 | GBP4 | KAT2B | MAPK14 | PDE8A | CD274 | TNFRSF1A |
| DDX58 | HMGB1 | GBP1 | SYK | BTK | CASP1 | GZMB | CDC37 |
| IFNG | CASP8 | NLRP6 | PTGER4 | CYLD | DPP9 | STAT3 | MYD88 |