FIG. 3.
Effect of a low inoculum on selection rates of E. coli strain REL606 harboring the plasmid pBGTEM-12 (size of inoculum, 103 CFU/ml), in competition with the isogenic REL607 strain harboring pBGTEM-1 (size of inoculum, 105 CFU/ml) in the presence of different cefotaxime concentrations. Selection rates after 4 h of challenge (a) and after 5 days of continuous challenge (b) with cefotaxime are shown. For each antibiotic concentration, results from four replicated experiments are represented.