Table 2.
GO-BP enrichment analysis of DEGs in co-expression modules of glomeruli
| Modules | The Number of DEGs | Go-BP Termsa | P-Value |
|---|---|---|---|
| Blue Module | 311 | GO:0070098:chemokine-mediated signaling pathway | 3.38E-09 |
| GO:0090026:positive regulation of monocyte chemotaxis | 5.93E-06 | ||
| GO:0071356:cellular response to tumor necrosis factor | 2.33E-05 | ||
| GO:0070374:positive regulation of ERK1 and ERK2 cascade | 2.66E-04 | ||
| GO:0002755:MyD88-dependent toll-like receptor signaling pathway | 2.52E-04 | ||
| Yellow Module | 28 | GO:0000122:negative regulation of transcription from RNA polymerase II promoter | 4.39E-06 |
| GO:0003151:outflow tract morphogenesis | 3.74E-05 | ||
| GO:0035050:embryonic heart tube development | 2.03E-04 | ||
| GO:0001570:vasculogenesis | 0.003 | ||
| Greenyellow Module | 19 | GO:0060337:type I interferon signaling pathway | 1.87E-11 |
| GO:0009615:response to virus | 4.54E-08 | ||
| GO:0051607:defense response to virus | 3.45E-07 | ||
| GO:0032728:positive regulation of interferon-beta production | 2.95E-04 | ||
| GO:0045087:innate immune response | 0.007 | ||
| Magenta Module | 5 | – | – |
| Turquoise Module | GO:0035435:phosphate ion transmembrane transport | 9.21E-04 | |
| GO:0035725:sodium ion transmembrane transport | 0.001 | ||
| GO:0006817:phosphate ion transport | 0.004 | ||
| Black Module | 25 | – | – |
| Tan Module | 1 | – | – |
| Purple Module | 0 | – | – |
aThe top five terms were displayed according to p-value