Table 3.
Associations of hormone, RANK pathway gene expression with volumetric percent density
| mRNA gene expression | Linear fold change | Lower confidence limit | Upper confidence limit | p value |
|---|---|---|---|---|
| PRL | 1.00 | 0.95 | 1.06 | 0.97 |
| ESR1 | 1.08 | 1.00 | 1.15 | 0.05 |
| PGR | 1.07 | 0.94 | 1.22 | 0.29 |
| STAT1 | 1.00 | 0.94 | 1.07 | 0.96 |
| STAT5 | 0.98 | 0.95 | 1.02 | 0.29 |
| RANK | 1.10 | 1.00 | 1.20 | 0.04 |
| RANKL | 1.10 | 0.94 | 1.29 | 0.26 |
| OPG | 1.10 | 0.94 | 1.28 | 0.23 |
| TNFRSF13B | 1.02 | 0.95 | 1.11 | 0.56 |
| TNFRSF18 | 1.04 | 1.00 | 1.09 | 0.04 |
Multivariable model adjusted for race (Non-Hispanic White, Black or African-American, Other), current age (continuous), BMI (continuous), age at first menarche (continuous), menopausal hormone therapy use (Yes, No, Missing), combined parity, and age at first birth (categorical)