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. 2022 Apr 14;9:19. doi: 10.1186/s40779-022-00378-z

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — CENPK expression is elevated in cervical cancer and confers poor patient prognosis. a Representative images showing the differential CENPK expression between cervical cancer and adjacent normal tissues. b Representative images showing the relationship between CENPK and Ki67 expression in cervical cancer. c Kaplan–Meier survival analysis disclosing the overall survival of cervical cancer patients according to CENPK expression. d Kaplan–Meier survival analysis displaying the recurrence-free survival of cervical cancer patients according to CENPK expression. e Univariate and multivariate analyses were adopted for correlating CENPK expression, clinicopathological characteristics, and overall survival of cervical cancer patients. f Univariate and multivariate analyses were performed to correlate CENPK expression, clinicopathological characteristics, and recurrence-free survival of cervical cancer patients. g Development of a nomogram for predicting cancer recurrence of cervical cancer patients. HR hazard ratio